STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21SPG21 abhydrolase domain containing, maspardin. (357 aa)    
Predicted Functional Partners:
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.829
SPG11
SPG11 vesicle trafficking associated, spatacsin.
   
  
 0.828
CD58
Uncharacterized protein.
      
 0.793
TNFSF15
TNF superfamily member 15.
      
 0.782
PAAF1
Proteasomal ATPase associated factor 1.
   
  
 0.780
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.768
SPART
Spartin.
      
 0.736
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
      
 0.722
NIPA1
NIPA magnesium transporter 1.
      
 0.718
LTF
Uncharacterized protein; Belongs to the transferrin family.
   
  
 0.699
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.