STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPB41L5Band 4.1-like protein 5; May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. (753 aa)    
Predicted Functional Partners:
RALB
RAS like proto-oncogene B.
   
 
 0.740
GLI2
GLI family zinc finger 2.
      
 0.564
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
   
  
 0.517
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
      
 0.515
SHROOM1
Shroom family member 1.
   
  
 0.498
KLHL8
Kelch like family member 8.
   
  
 0.482
NCOR2
Nuclear receptor corepressor 2.
      
 0.480
CNOT9
CCR4-NOT transcription complex subunit 9.
      
 0.457
KDM6A
Lysine demethylase 6A.
   
  
 0.442
SULT4A1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.410
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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