STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN1Sidoreflexin. (324 aa)    
Predicted Functional Partners:
MTRF1
Mitochondrial translation release factor 1.
   
  
 0.795
PRELID1
PRELI domain containing 1.
   
  
 0.743
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
   
  
 0.743
AK4
DnaJ heat shock protein family (Hsp40) member C6.
      
 0.717
FBXL4
F-box and leucine rich repeat protein 4.
   
  
 0.660
LEPROT
Uncharacterized protein.
   
 
 0.597
CCNC
Cyclin C; Belongs to the cyclin family.
   
  
 0.574
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.573
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
    
 
 0.573
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
  
 0.572
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.