STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)    
Predicted Functional Partners:
RABGAP1
RAB GTPase activating protein 1.
   
  
 0.881
CNOT1
CCR4-NOT transcription complex subunit 1.
   
 
 0.820
HELZ
Helicase with zinc finger.
   
 
 0.788
ATXN2L
Ataxin 2 like.
   
 
 0.786
XRN1
5'-3' exoribonuclease 1.
   
 
 0.719
AFF4
AF4/FMR2 family member 4.
   
 
 0.718
LTN1
Listerin E3 ubiquitin protein ligase 1.
   
  
 0.705
MYSM1
Myb like, SWIRM and MPN domains 1.
   
   0.702
TRIP12
Thyroid hormone receptor interactor 12.
   
    0.686
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.677
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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