NUP50 protein (Canis lupus familiaris) - STRING interaction network

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Score

NUP50

Nucleoporin 50. (523 aa)

Predicted Functional Partners:

NUP153

0.993

LOC100686305

0.983

NUP43

0.973

RAN

0.973

NUP214

0.956

NUP107

0.941

NUP133

0.941

NUP93

0.924

KPNA1

0.922

NUP85

0.919

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KPNA1	NUP153	ENSCAFP00000017554	ENSCAFP00000014907	Importin subunit alpha; Functions in nuclear protein import.	Nucleoporin 153.	0.559
KPNA1	NUP50	ENSCAFP00000017554	ENSCAFP00000064907	Importin subunit alpha; Functions in nuclear protein import.	Nucleoporin 50.	0.922
KPNA1	NUP85	ENSCAFP00000017554	ENSCAFP00000007050	Importin subunit alpha; Functions in nuclear protein import.	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.429
KPNA1	RAN	ENSCAFP00000017554	ENSCAFP00000009963	Importin subunit alpha; Functions in nuclear protein import.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.403
LOC100686305	NUP107	ENSCAFP00000048537	ENSCAFP00000000604	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.545
LOC100686305	NUP133	ENSCAFP00000048537	ENSCAFP00000017925	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 133.	0.483
LOC100686305	NUP153	ENSCAFP00000048537	ENSCAFP00000014907	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 153.	0.987
LOC100686305	NUP214	ENSCAFP00000048537	ENSCAFP00000029512	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 214.	0.788
LOC100686305	NUP43	ENSCAFP00000048537	ENSCAFP00000000567	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 43.	0.453
LOC100686305	NUP50	ENSCAFP00000048537	ENSCAFP00000064907	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 50.	0.983
LOC100686305	NUP85	ENSCAFP00000048537	ENSCAFP00000007050	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.537
LOC100686305	NUP93	ENSCAFP00000048537	ENSCAFP00000013384	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.517
LOC100686305	RAN	ENSCAFP00000048537	ENSCAFP00000009963	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.900
NUP107	LOC100686305	ENSCAFP00000000604	ENSCAFP00000048537	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.545
NUP107	NUP133	ENSCAFP00000000604	ENSCAFP00000017925	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 133.	0.999
NUP107	NUP153	ENSCAFP00000000604	ENSCAFP00000014907	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 153.	0.984
NUP107	NUP214	ENSCAFP00000000604	ENSCAFP00000029512	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 214.	0.991
NUP107	NUP43	ENSCAFP00000000604	ENSCAFP00000000567	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 43.	0.999
NUP107	NUP50	ENSCAFP00000000604	ENSCAFP00000064907	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nucleoporin 50.	0.941
NUP107	NUP85	ENSCAFP00000000604	ENSCAFP00000007050	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.999