STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAV1Salvador family WW domain containing protein 1. (384 aa)    
Predicted Functional Partners:
STK4
Serine/threonine kinase 4.
    
 0.986
STK3
Serine/threonine kinase 3.
   
 0.984
LATS2
Non-specific serine/threonine protein kinase.
   
 0.981
LATS1
Large tumor suppressor kinase 1.
    
 0.979
MOB1A
MOB kinase activator 1A.
    
 0.968
LIMD1
LIM domains containing 1.
   
 0.942
AJUBA
Ajuba LIM protein.
   
 0.919
MOB1B
MOB kinase activator 1B.
    
 0.829
AMOTL2
Angiomotin like 2.
    
 0.784
FRMD6
FERM domain containing 6.
   
 
 0.767
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.