STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000064931Adenylyl cyclase-associated protein; Belongs to the CAP family. (363 aa)    
Predicted Functional Partners:
DBNL
Drebrin like.
   
 
 0.591
DBN1
Drebrin 1.
   
 
 0.591
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.566
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 
 0.551
AP1G1
PH domain and leucine rich repeat protein phosphatase 2.
    
 
 0.551
GRXCR1
Glutaredoxin and cysteine rich domain containing 1.
    
   0.529
TLR9
Twinfilin actin binding protein 2.
    
 
 0.524
TWF1
Twinfilin actin binding protein 1.
    
 
 0.524
WDR1
WD repeat domain 1.
   
 
 0.506
PDC
Phosducin; Inhibits the transcriptional activation activity of the cone- rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism.
      
 0.487
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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