STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND2ADENN domain containing 2A. (1134 aa)    
Predicted Functional Partners:
RAB9B
RAB9B, member RAS oncogene family.
     
 0.848
RHOBTB3
Rho related BTB domain containing 3.
      
 0.790
RAB9A
Ras-related protein Rab-9A; Involved in the transport of proteins between the endosomes and the trans-Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity). Belongs to the small GTPase superfamily. Rab family.
     
 0.695
AVL9
AVL9 cell migration associated.
      
 0.622
KDM7A
Lysine demethylase 7A.
    
 
 0.576
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.554
RAB35
RAB35, member RAS oncogene family.
    
 
 0.529
IFT27
Intraflagellar transport 27.
   
 
 0.520
NMT1
Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.
      
 0.515
DENND1B
DENN domain containing 1B.
    
 
0.504
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.