STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (954 aa)    
Predicted Functional Partners:
GPR89A
Uncharacterized protein.
 
 
    0.821
ESYT2
Extended synaptotagmin 2.
   
 
 0.703
IFRD2
Interferon related developmental regulator 2.
      
 0.688
MBLAC2
Metallo-beta-lactamase domain containing 2.
      
 0.684
GFM2
Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
  
 0.668
ARHGEF38
Rho guanine nucleotide exchange factor 38.
   
  
 0.637
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
      
 0.611
SMCO2
Single-pass membrane protein with coiled-coil domains 2.
      
 0.570
DPY19L1
Dpy-19 like C-mannosyltransferase 1.
   
  
 0.568
SH3RF1
SH3 domain containing ring finger 1.
   
  
 0.546
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.