STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VSTM5V-set and transmembrane domain containing 5. (552 aa)    
Predicted Functional Partners:
GPR176
G protein-coupled receptor 176.
      
 0.830
ANKRD55
Ankyrin repeat domain 55.
      
 0.691
MED17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.687
GALR1
Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.679
DHRS7C
Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.563
WDR27
WD repeat domain 27.
      
 0.528
KCNIP2
Potassium voltage-gated channel interacting protein 2.
      
 0.524
KCNIP4
Potassium voltage-gated channel interacting protein 4.
      
 0.524
LRRN3
Leucine rich repeat neuronal 3.
      
 0.515
LRATD1
LRAT domain containing 1.
      
 0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.