STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000065322SKA2 domain-containing protein. (59 aa)    
Predicted Functional Partners:
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 
 0.914
SKA1
Spindle and kinetochore associated complex subunit 1.
   
 
 0.912
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.554
OTULIN
OTU deubiquitinase with linear linkage specificity.
      
 0.515
GAS2L1
Growth arrest specific 2 like 1.
      
 0.509
SAC3D1
SAC3 domain containing 1.
      
 0.497
PRR11
Proline rich 11.
      
 0.483
BUB3
BUB3 mitotic checkpoint protein.
      
 0.478
RCBTB1
RCC1 and BTB domain containing protein 1.
      
 0.459
PLK1
Serine/threonine-protein kinase PLK.
   
  
 0.413
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.