STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPX2TPX2 microtubule nucleation factor. (755 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.976
NUSAP1
Nucleolar and spindle associated protein 1.
   
  
 0.924
CENPM
Centromere protein M.
   
  
 0.827
COG5
Component of oligomeric golgi complex 5.
   
 
 0.820
CBY2
Component of oligomeric golgi complex 3.
    
 
 0.815
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.813
COG2
Component of oligomeric golgi complex 2.
   
 
 0.813
COG1
Component of oligomeric golgi complex 1.
    
 
 0.811
TACC3
Transforming acidic coiled-coil containing protein 3.
   
 
 0.806
CENPN
Centromere protein N.
   
  
 0.806
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.