STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLC1Modulator of VRAC current 1. (724 aa)    
Predicted Functional Partners:
SLC2A4RG
SLC2A4 regulator.
      
 0.787
CDC14B
Cell division cycle 14B.
      
 0.721
ACTRT1
Actin related protein T1; Belongs to the actin family.
   
  
 0.648
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
      
 0.568
MPPE1
Metallophosphoesterase 1.
      
 0.560
TBXA2R
Thromboxane A2 receptor.
   
  
 0.558
GLTP
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.517
ATP1B1
Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
   
 
 0.510
TMEM200A
Transmembrane protein 200A.
      
 0.457
GON4L
Myb-like domain-containing protein.
      
 0.454
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.