STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLP1Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. (320 aa)    
Predicted Functional Partners:
PLP2
MARVEL domain-containing protein.
   
 
 0.970
MBP
Myelin basic protein.
   
 
 0.913
SOX10
SRY-box transcription factor 10.
   
  
 0.863
MYRF
Myelin regulatory factor.
      
 0.856
MAG
Myelin associated glycoprotein.
   
 
 0.843
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.811
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase.
   
  
 0.788
MOBP
Myelin associated oligodendrocyte basic protein.
   
  
 0.784
MOG
Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion. Belongs to the immunoglobulin superfamily. BTN/MOG family.
   
  
 0.769
OLIG2
Oligodendrocyte transcription factor 2.
   
  
 0.713
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.