| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SMAD1 | SMAD2 | ENSCAFP00000011384 | ENSCAFP00000065569 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.995 |
| SMAD1 | SMAD3 | ENSCAFP00000011384 | ENSCAFP00000025647 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.995 |
| SMAD1 | SMAD4 | ENSCAFP00000011384 | ENSCAFP00000052646 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD1 | SMAD5 | ENSCAFP00000011384 | ENSCAFP00000001536 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD1 | SMAD6 | ENSCAFP00000011384 | ENSCAFP00000025538 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.997 |
| SMAD1 | SMAD9 | ENSCAFP00000011384 | ENSCAFP00000009257 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.998 |
| SMAD1 | SMURF2 | ENSCAFP00000011384 | ENSCAFP00000049702 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.964 |
| SMAD1 | TGFBR1 | ENSCAFP00000011384 | ENSCAFP00000040830 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.724 |
| SMAD1 | TGFBR2 | ENSCAFP00000011384 | ENSCAFP00000063016 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.545 |
| SMAD1 | ZFYVE9 | ENSCAFP00000011384 | ENSCAFP00000048955 | Mothers against decapentaplegic homolog. | Zinc finger FYVE domain-containing protein. | 0.524 |
| SMAD2 | SMAD1 | ENSCAFP00000065569 | ENSCAFP00000011384 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.995 |
| SMAD2 | SMAD3 | ENSCAFP00000065569 | ENSCAFP00000025647 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.997 |
| SMAD2 | SMAD4 | ENSCAFP00000065569 | ENSCAFP00000052646 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD5 | ENSCAFP00000065569 | ENSCAFP00000001536 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.976 |
| SMAD2 | SMAD6 | ENSCAFP00000065569 | ENSCAFP00000025538 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.994 |
| SMAD2 | SMAD9 | ENSCAFP00000065569 | ENSCAFP00000009257 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.990 |
| SMAD2 | SMURF2 | ENSCAFP00000065569 | ENSCAFP00000049702 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.986 |
| SMAD2 | TGFBR1 | ENSCAFP00000065569 | ENSCAFP00000040830 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.994 |
| SMAD2 | TGFBR2 | ENSCAFP00000065569 | ENSCAFP00000063016 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.987 |
| SMAD2 | ZFYVE9 | ENSCAFP00000065569 | ENSCAFP00000048955 | Mothers against decapentaplegic homolog. | Zinc finger FYVE domain-containing protein. | 0.986 |
