STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1R17Protein phosphatase 1 regulatory subunit 17. (305 aa)    
Predicted Functional Partners:
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.668
IKZF2
IKAROS family zinc finger 2.
      
 0.596
STRC
Stereocilin.
      
 0.534
NEUROD6
Neurogenic differentiation factor.
   
  
 0.523
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor.
      
 0.515
ISL1
ISL LIM homeobox 1.
      
 0.505
CLRN2
Clarin 2.
      
 0.499
PMM1
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
      
 0.495
ENSCAFP00000061191
Uncharacterized protein.
      
 0.495
LRRC71
Leucine rich repeat containing 71.
      
 0.491
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.