STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALPLAlkaline phosphatase. (572 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
   
 
  0.902
NTPCR
Uncharacterized protein.
     
  0.900
PTS
6-pyruvoyltetrahydropterin synthase.
     
  0.900
TPK1
Thiamin pyrophosphokinase 1.
     
  0.900
PSAT1
Phosphoserine aminotransferase.
   
 
 0.805
RUNX2
RUNX family transcription factor 2.
   
  
 0.782
NADK
NAD kinase.
   
 
  0.777
SP7
Sp7 transcription factor.
   
  
 0.728
IBSP
Integrin binding sialoprotein.
   
  
 0.724
COL1A1
Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).
   
  
 0.723
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.