node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AR | CREBBP | ENSCAFP00000024499 | ENSCAFP00000036447 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | CREB binding protein. | 0.726 |
AR | EP300 | ENSCAFP00000024499 | ENSCAFP00000001585 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | E1A binding protein p300. | 0.678 |
AR | ESR1 | ENSCAFP00000024499 | ENSCAFP00000000624 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.656 |
AR | NCOA1 | ENSCAFP00000024499 | ENSCAFP00000006049 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Nuclear receptor coactivator. | 0.857 |
AR | NCOA2 | ENSCAFP00000024499 | ENSCAFP00000065782 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Nuclear receptor coactivator 2. | 0.972 |
AR | NR3C1 | ENSCAFP00000024499 | ENSCAFP00000009468 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Nuclear receptor subfamily 3 group C member 1. | 0.603 |
CREBBP | AR | ENSCAFP00000036447 | ENSCAFP00000024499 | CREB binding protein. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.726 |
CREBBP | EP300 | ENSCAFP00000036447 | ENSCAFP00000001585 | CREB binding protein. | E1A binding protein p300. | 0.995 |
CREBBP | ESR1 | ENSCAFP00000036447 | ENSCAFP00000000624 | CREB binding protein. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.893 |
CREBBP | KAT6A | ENSCAFP00000036447 | ENSCAFP00000008454 | CREB binding protein. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.651 |
CREBBP | NCOA1 | ENSCAFP00000036447 | ENSCAFP00000006049 | CREB binding protein. | Nuclear receptor coactivator. | 0.992 |
CREBBP | NCOA2 | ENSCAFP00000036447 | ENSCAFP00000065782 | CREB binding protein. | Nuclear receptor coactivator 2. | 0.956 |
CREBBP | NR3C1 | ENSCAFP00000036447 | ENSCAFP00000009468 | CREB binding protein. | Nuclear receptor subfamily 3 group C member 1. | 0.691 |
CREBBP | RXRA | ENSCAFP00000036447 | ENSCAFP00000058322 | CREB binding protein. | Retinoid X receptor alpha. | 0.902 |
CREBBP | RXRB | ENSCAFP00000036447 | ENSCAFP00000001304 | CREB binding protein. | Retinoic acid receptor RXR-beta; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE); Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.780 |
CREBBP | THRB | ENSCAFP00000036447 | ENSCAFP00000045245 | CREB binding protein. | Thyroid hormone receptor beta. | 0.702 |
EP300 | AR | ENSCAFP00000001585 | ENSCAFP00000024499 | E1A binding protein p300. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.678 |
EP300 | CREBBP | ENSCAFP00000001585 | ENSCAFP00000036447 | E1A binding protein p300. | CREB binding protein. | 0.995 |
EP300 | ESR1 | ENSCAFP00000001585 | ENSCAFP00000000624 | E1A binding protein p300. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.949 |
EP300 | KAT6A | ENSCAFP00000001585 | ENSCAFP00000008454 | E1A binding protein p300. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.891 |