STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS27Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (458 aa)    
Predicted Functional Partners:
GRINA
Glutamate ionotropic receptor NMDA type subunit associated protein 1.
   
  
 0.779
NEFH
Neurofilament heavy; Belongs to the intermediate filament family.
    
 
 0.755
R3HDM2
Uncharacterized protein.
      
 0.716
HOXA7
Homeobox A7.
   
  
 0.710
SFN
Stratifin; Belongs to the 14-3-3 family.
   
 
 0.704
CD3EAP
CD3e molecule associated protein.
    
 
 0.676
ATRNL1
Attractin like 1.
   
  
 0.614
BAIAP2L1
BAI1 associated protein 2 like 1.
      
 0.604
COX18
Cytochrome c oxidase assembly factor COX18.
    
 
 0.578
POU2F2
POU domain protein.
      
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.