STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS1Protein inhibitor of activated STAT 1. (655 aa)    
Predicted Functional Partners:
STAT1
Signal transducer and activator of transcription.
   
 0.989
STAT2
Signal transducer and activator of transcription.
   
 0.941
STAT3
Signal transducer and activator of transcription.
   
 0.896
SUMO2
Small ubiquitin-related modifier.
    
 0.879
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.878
STAT5B
Signal transducer and activator of transcription.
   
 0.846
SUMO1
Rad60-SLD domain-containing protein.
   
 
 0.826
STAT5A
Signal transducer and activator of transcription.
   
 0.808
STAT4
Signal transducer and activator of transcription.
   
 0.802
ZNF133
Zinc finger protein 133.
    
 
 0.789
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.