STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABL2Tyrosine-protein kinase. (1148 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
0.974
CRKL
CRK like proto-oncogene, adaptor protein.
   
0.963
RIN1
Ras and Rab interactor 1.
    
 0.952
ABL1
Tyrosine-protein kinase.
  
0.932
RAC2
Rac family small GTPase 2.
   
 0.917
RAC3
Uncharacterized protein.
   
 0.917
ABI1
Abl interactor 1.
    
 
 0.784
TBL2
Transducin beta like 2.
   
 
 0.672
ABI2
Abl interactor 2.
   
 
 0.650
CBL
Cbl proto-oncogene.
   
 
 0.639
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.