STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (200 aa)    
Predicted Functional Partners:
LIMK1
LIM domain kinase 1.
   
 0.985
SSH1
Slingshot protein phosphatase 1.
   
 0.966
SSH3
Slingshot protein phosphatase 3.
    
 0.953
SSH2
Slingshot protein phosphatase 2.
    
 0.942
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
  
0.926
F1Q1C8_CANLF
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
  
  
 
0.901
LOC106558389
Profilin; Belongs to the profilin family.
   
 
 0.838
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.838
PFN2
Profilin; Belongs to the profilin family.
   
 
 0.837
LIMK2
LIM domain kinase 2.
   
 
 0.834
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.