EGFL8 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

EGFL8

EGF like domain multiple 8. (338 aa)

Predicted Functional Partners:

CPNE3

0.788

ERBIN

0.698

GPR37L1

0.680

PCDH20

0.669

PTPN12

0.626

PPT2

0.610

PSAP

0.563

SKIV2L

0.530

ZKSCAN8

0.491

CLDN5

0.481

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN5	EGFL8	ENSCAFP00000045788	ENSCAFP00000066438	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	EGF like domain multiple 8.	0.481
CPNE3	EGFL8	ENSCAFP00000013053	ENSCAFP00000066438	Copine 3.	EGF like domain multiple 8.	0.788
CPNE3	ERBIN	ENSCAFP00000013053	ENSCAFP00000064102	Copine 3.	Erbb2 interacting protein.	0.685
CPNE3	PTPN12	ENSCAFP00000013053	ENSCAFP00000063672	Copine 3.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.608
EGFL8	CLDN5	ENSCAFP00000066438	ENSCAFP00000045788	EGF like domain multiple 8.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.481
EGFL8	CPNE3	ENSCAFP00000066438	ENSCAFP00000013053	EGF like domain multiple 8.	Copine 3.	0.788
EGFL8	ERBIN	ENSCAFP00000066438	ENSCAFP00000064102	EGF like domain multiple 8.	Erbb2 interacting protein.	0.698
EGFL8	GPR37L1	ENSCAFP00000066438	ENSCAFP00000034693	EGF like domain multiple 8.	G protein-coupled receptor 37 like 1.	0.680
EGFL8	PCDH20	ENSCAFP00000066438	ENSCAFP00000007352	EGF like domain multiple 8.	Protocadherin 20.	0.669
EGFL8	PPT2	ENSCAFP00000066438	ENSCAFP00000001092	EGF like domain multiple 8.	Palmitoyl-protein thioesterase 2.	0.610
EGFL8	PSAP	ENSCAFP00000066438	ENSCAFP00000021252	EGF like domain multiple 8.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.563
EGFL8	PTPN12	ENSCAFP00000066438	ENSCAFP00000063672	EGF like domain multiple 8.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.626
EGFL8	SKIV2L	ENSCAFP00000066438	ENSCAFP00000000965	EGF like domain multiple 8.	Ski2 like RNA helicase.	0.530
EGFL8	ZKSCAN8	ENSCAFP00000066438	ENSCAFP00000017045	EGF like domain multiple 8.	Zinc finger with KRAB and SCAN domains 8.	0.491
ERBIN	CPNE3	ENSCAFP00000064102	ENSCAFP00000013053	Erbb2 interacting protein.	Copine 3.	0.685
ERBIN	EGFL8	ENSCAFP00000064102	ENSCAFP00000066438	Erbb2 interacting protein.	EGF like domain multiple 8.	0.698
ERBIN	PTPN12	ENSCAFP00000064102	ENSCAFP00000063672	Erbb2 interacting protein.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.578
GPR37L1	EGFL8	ENSCAFP00000034693	ENSCAFP00000066438	G protein-coupled receptor 37 like 1.	EGF like domain multiple 8.	0.680
GPR37L1	PSAP	ENSCAFP00000034693	ENSCAFP00000021252	G protein-coupled receptor 37 like 1.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.950
PCDH20	EGFL8	ENSCAFP00000007352	ENSCAFP00000066438	Protocadherin 20.	EGF like domain multiple 8.	0.669