node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUB1B | ESPL1 | ENSCAFP00000013122 | ENSCAFP00000010445 | BUB1 mitotic checkpoint serine/threonine kinase B. | Extra spindle pole bodies like 1, separase. | 0.950 |
BUB1B | HJURP | ENSCAFP00000013122 | ENSCAFP00000036068 | BUB1 mitotic checkpoint serine/threonine kinase B. | Holliday junction recognition protein. | 0.880 |
BUB1B | IQGAP3 | ENSCAFP00000013122 | ENSCAFP00000066484 | BUB1 mitotic checkpoint serine/threonine kinase B. | IQ motif containing GTPase activating protein 3. | 0.783 |
BUB1B | KIF20A | ENSCAFP00000013122 | ENSCAFP00000001720 | BUB1 mitotic checkpoint serine/threonine kinase B. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.959 |
BUB1B | MKI67 | ENSCAFP00000013122 | ENSCAFP00000019524 | BUB1 mitotic checkpoint serine/threonine kinase B. | Marker of proliferation Ki-67. | 0.910 |
CDC42-2 | IQGAP1 | ENSCAFP00000060180 | ENSCAFP00000018867 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | IQ motif containing GTPase activating protein 1. | 0.981 |
CDC42-2 | IQGAP2 | ENSCAFP00000060180 | ENSCAFP00000060498 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | IQ motif containing GTPase activating protein 2. | 0.965 |
CDC42-2 | IQGAP3 | ENSCAFP00000060180 | ENSCAFP00000066484 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | IQ motif containing GTPase activating protein 3. | 0.949 |
CDC42-2 | RAC2 | ENSCAFP00000060180 | ENSCAFP00000002174 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.919 |
CDC42-2 | RAC3 | ENSCAFP00000060180 | ENSCAFP00000008868 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.925 |
ESPL1 | BUB1B | ENSCAFP00000010445 | ENSCAFP00000013122 | Extra spindle pole bodies like 1, separase. | BUB1 mitotic checkpoint serine/threonine kinase B. | 0.950 |
ESPL1 | HJURP | ENSCAFP00000010445 | ENSCAFP00000036068 | Extra spindle pole bodies like 1, separase. | Holliday junction recognition protein. | 0.864 |
ESPL1 | IQGAP3 | ENSCAFP00000010445 | ENSCAFP00000066484 | Extra spindle pole bodies like 1, separase. | IQ motif containing GTPase activating protein 3. | 0.818 |
ESPL1 | KIF20A | ENSCAFP00000010445 | ENSCAFP00000001720 | Extra spindle pole bodies like 1, separase. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.952 |
ESPL1 | MKI67 | ENSCAFP00000010445 | ENSCAFP00000019524 | Extra spindle pole bodies like 1, separase. | Marker of proliferation Ki-67. | 0.902 |
HJURP | BUB1B | ENSCAFP00000036068 | ENSCAFP00000013122 | Holliday junction recognition protein. | BUB1 mitotic checkpoint serine/threonine kinase B. | 0.880 |
HJURP | ESPL1 | ENSCAFP00000036068 | ENSCAFP00000010445 | Holliday junction recognition protein. | Extra spindle pole bodies like 1, separase. | 0.864 |
HJURP | IQGAP3 | ENSCAFP00000036068 | ENSCAFP00000066484 | Holliday junction recognition protein. | IQ motif containing GTPase activating protein 3. | 0.822 |
HJURP | KIF20A | ENSCAFP00000036068 | ENSCAFP00000001720 | Holliday junction recognition protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.945 |
HJURP | MKI67 | ENSCAFP00000036068 | ENSCAFP00000019524 | Holliday junction recognition protein. | Marker of proliferation Ki-67. | 0.895 |