STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (303 aa)    
Predicted Functional Partners:
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13.
      
 0.846
AK4
DnaJ heat shock protein family (Hsp40) member C6.
   
 
 0.814
PTPRN
Protein tyrosine phosphatase receptor type N.
    
 
 0.812
HSPB8
Heat shock protein beta-8; Displays temperature-dependent chaperone activity. Belongs to the small heat shock protein (HSP20) family.
   
 
 0.730
HSPA4
Heat shock 70 kDa protein 4.
   
 0.713
TUBA4A
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
 
 
 
 0.667
HSPA4L
Heat shock protein family A (Hsp70) member 4 like.
   
 0.609
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
  
 
 
0.603
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.588
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
 0.579
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.