STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM165Transmembrane protein 165. (476 aa)    
Predicted Functional Partners:
NCBP2
Mannosyltransferase.
   
  
 0.774
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
      
 0.694
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
  
 0.694
SYVN1
Synoviolin 1.
   
  
 0.681
AMFR
Autocrine motility factor receptor.
   
  
 0.678
DERL2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
  
 0.678
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
   
 
 0.677
B4GALT6
Beta-1,4-galactosyltransferase 6.
      
 0.677
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
   
  
 0.663
CCDC22
Coiled-coil domain containing 22.
   
  
 0.659
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.