close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFAP1Actin filament-associated protein 1 isoform X4. (818 aa)    
Predicted Functional Partners:
ACTL7A
Actin-like protein 7A; Belongs to the actin family.
    
 
 0.752
SH3TC1
LOW QUALITY PROTEIN: SH3 domain and tetratricopeptide repeat-containing protein 1.
      
 0.696
ABLIM2
Actin-binding LIM protein 2 isoform X4.
      
 0.603
NIPSNAP2
Protein NipSnap homolog 2.
      
 0.539
RBM28
RNA-binding protein 28 isoform X1.
      
 0.538
KIF22
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.525
ENSVVUP00000038618
annotation not available
      
 0.518
TMEM70
Transmembrane protein 70, mitochondrial.
      
 0.514
SRC
Tyrosine-protein kinase.
    
 
 0.487
GMDS
GDP-mannose 4,6 dehydratase.
      
 0.485
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (16%) [HD]