STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC8DNA excision repair protein ERCC-8 isoform X2. (469 aa)    
Predicted Functional Partners:
DDB1
DNA damage-binding protein 1.
    
 0.996
RBX1
E3 ubiquitin-protein ligase RBX1 isoform X2.
    
 0.989
ERCC6
DNA excision repair protein ERCC-6 isoform X1.
    
 0.987
CUL4A
cullin-4A; Belongs to the cullin family.
    
 0.957
COP1
E3 ubiquitin-protein ligase COP1.
    
  0.954
UVSSA
UV-stimulated scaffold protein A isoform X1.
    
 
 0.934
CUL4B
cullin-4B isoform X2; Belongs to the cullin family.
    
 0.931
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.925
DET1
DET1 homolog isoform X4.
     
  0.900
ERCC3
General transcription and DNA repair factor IIH helicase subunit XPB.
     
 0.872
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.