close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RARARetinoic acid receptor alpha isoform X2. (500 aa)    
Predicted Functional Partners:
RXRA
Retinoic acid receptor RXR-alpha isoform X1.
   
0.996
PML
Protein PML.
    
 0.959
RXRG
Retinoic acid receptor RXR-gamma.
   
0.943
ZBTB16
Zinc finger and BTB domain-containing protein 16.
    
 0.934
RXRB
Retinoic acid receptor RXR-beta.
   
0.933
SPI1
Transcription factor PU.1 isoform X1.
    
 0.908
NCOR1
Nuclear receptor corepressor 1 isoform X5.
    
 0.774
NCOR2
Nuclear receptor corepressor 2 isoform X9.
    
 0.740
PROP1
Homeobox protein prophet of Pit-1.
    
 
 0.672
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.657
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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