close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSPO3R-spondin-3 isoform X1. (279 aa)    
Predicted Functional Partners:
LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4.
   
 0.987
LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5.
   
 0.980
RNF43
E3 ubiquitin-protein ligase RNF43.
   
 0.979
LGR6
Leucine-rich repeat-containing G-protein coupled receptor 6.
    
 0.956
RSPO2
R-spondin-2.
  
  
 
0.953
ZNRF3
E3 ubiquitin-protein ligase ZNRF3.
   
 0.949
RSPO1
R-spondin-1.
  
  
 
0.912
WNT2B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.613
WRN
Werner syndrome ATP-dependent helicase.
     
 0.563
FOXL1
Forkhead box protein L1.
     
 0.543
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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