JPH3 protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

JPH3

Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (754 aa)

Predicted Functional Partners:

TRDN

0.681

GINS2

0.605

NOB1

0.603

ATN1

0.592

CASQ1

0.570

CASQ2

0.533

HSDL1

0.533

ACTR5

0.525

LOC112934124

0.518

STIM1

0.510

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR5	JPH3	ENSVVUP00000041105	ENSVVUP00000001099	Actin-related protein 5; Belongs to the actin family.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.525
ATN1	JPH3	ENSVVUP00000014959	ENSVVUP00000001099	Atrophin-1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.592
CASQ1	CASQ2	ENSVVUP00000022002	ENSVVUP00000014051	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.920
CASQ1	JPH3	ENSVVUP00000022002	ENSVVUP00000001099	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.570
CASQ1	STIM1	ENSVVUP00000022002	ENSVVUP00000036055	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Stromal interaction molecule 1 isoform X2.	0.504
CASQ1	TRDN	ENSVVUP00000022002	ENSVVUP00000000450	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Triadin.	0.991
CASQ2	CASQ1	ENSVVUP00000014051	ENSVVUP00000022002	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.920
CASQ2	JPH3	ENSVVUP00000014051	ENSVVUP00000001099	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.533
CASQ2	STIM1	ENSVVUP00000014051	ENSVVUP00000036055	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Stromal interaction molecule 1 isoform X2.	0.448
CASQ2	TRDN	ENSVVUP00000014051	ENSVVUP00000000450	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Triadin.	0.992
GINS2	HSDL1	ENSVVUP00000000483	ENSVVUP00000042614	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.741
GINS2	JPH3	ENSVVUP00000000483	ENSVVUP00000001099	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.605
HSDL1	GINS2	ENSVVUP00000042614	ENSVVUP00000000483	Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.741
HSDL1	JPH3	ENSVVUP00000042614	ENSVVUP00000001099	Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.533
JPH3	ACTR5	ENSVVUP00000001099	ENSVVUP00000041105	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Actin-related protein 5; Belongs to the actin family.	0.525
JPH3	ATN1	ENSVVUP00000001099	ENSVVUP00000014959	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Atrophin-1.	0.592
JPH3	CASQ1	ENSVVUP00000001099	ENSVVUP00000022002	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.570
JPH3	CASQ2	ENSVVUP00000001099	ENSVVUP00000014051	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.533
JPH3	GINS2	ENSVVUP00000001099	ENSVVUP00000000483	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.605
JPH3	HSDL1	ENSVVUP00000001099	ENSVVUP00000042614	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.533

page 1 of 2

Server load: medium (56%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About