close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC4Kelch domain-containing protein 4 isoform X1. (554 aa)    
Predicted Functional Partners:
ARMC6
Armadillo repeat-containing protein 6.
      
 0.693
ZNF185
Zinc finger protein 185.
      
 0.606
DMAC1
Distal membrane-arm assembly complex protein 1 isoform X2.
      
 0.606
DHRS11
Dehydrogenase/reductase SDR family member 11 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.604
SYTL3
Synaptotagmin-like protein 3.
      
 0.603
RBMS2
RNA-binding motif, single-stranded-interacting protein 2 isoform X2.
      
 0.603
TMEM41B
Transmembrane protein 41B.
      
 0.603
ARMC7
Armadillo repeat containing 7.
      
 0.538
CPXM1
Probable carboxypeptidase X1.
      
 0.523
UTP6
U3 small nucleolar RNA-associated protein 6 homolog.
   
    0.522
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (28%) [HD]