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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASC3Protein CASC3. (703 aa)    
Predicted Functional Partners:
RBM8A
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.999
EIF4A3
Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.
    
 0.999
UPF1
Regulator of nonsense transcripts 1 isoform X2.
    
 0.985
UPF2
Regulator of nonsense transcripts 2 isoform X1.
    
 0.922
UPF3B
Regulator of nonsense transcripts 3B isoform X2.
    
 0.919
MAGOH
Protein mago nashi homolog.
    
 0.910
MAGOHB
Protein mago nashi homolog 2.
    
 0.910
LOC112908264
Protein mago nashi homolog.
    
 0.910
UPF3A
Regulator of nonsense transcripts 3A isoform X1.
    
 0.878
ENSVVUP00000025427
annotation not available
    
 0.866
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.