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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM22Disintegrin and metalloproteinase domain-containing protein 22 isoform X15. (785 aa)    
Predicted Functional Partners:
LGI1
Leucine-rich glioma-inactivated protein 1 isoform X1.
    
 0.974
DLG4
Disks large homolog 4 isoform X5; Belongs to the MAGUK family.
   
 0.953
LGI2
Leucine-rich repeat LGI family member 2.
     
 0.936
LGI4
Leucine-rich repeat LGI family member 4.
     
 0.935
LGI3
Leucine-rich repeat LGI family member 3.
     
 0.816
NFASC
Neurofascin isoform X3.
      
 0.725
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 
 0.676
TEX47
Testis-expressed protein 47.
      
 0.625
DLG1
Disks large homolog 1 isoform X3; Belongs to the MAGUK family.
   
 0.573
DLG2
Disks large homolog 2 isoform X4.
   
 0.573
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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