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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ8ATP-sensitive inward rectifier potassium channel 8. (424 aa)    
Predicted Functional Partners:
ABCC9
ATP-binding cassette sub-family C member 9 isoform X1.
   
 0.984
ABCC8
ATP-binding cassette sub-family C member 8 isoform X4.
 
 
 0.955
PRKCE
Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]
     
  0.900
SCN3B
Sodium channel subunit beta-3 isoform X2.
   
  
 0.621
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2 isoform X4.
      
 0.607
GPD1L
Glycerol-3-phosphate dehydrogenase [NAD(+)].
      
 0.607
SCN1B
Sodium channel subunit beta-1.
      
 0.607
CACNA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X5.
      
 0.607
DPP6
Dipeptidyl aminopeptidase-like protein 6; Belongs to the peptidase S9B family.
      
 0.603
BRS3
Bombesin receptor subtype-3; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.549
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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