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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTSR2Neurotensin receptor type 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (285 aa)    
Predicted Functional Partners:
NTS
Neurotensin/neuromedin N.
    
 0.997
NTSR1
Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family.
     
0.949
NDRG4
Protein NDRG4 isoform X1.
   
  
 0.625
NPS
Neuropeptide S.
     
 0.606
NMU
neuromedin-U.
    
 0.582
EDN1
Endothelin-1.
    
 0.579
EDN3
Endothelin-3 isoform X1.
    
  0.567
COPA
Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
     
 0.551
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
 0.550
SLCO1C1
Solute carrier organic anion transporter family member.
   
  
 0.547
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.