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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP27A1Sterol 26-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (530 aa)    
Predicted Functional Partners:
CYP7B1
25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family.
  
  
0.966
CYP8B1
5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family.
     
0.959
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.959
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
0.951
CYP46A1
Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family.
  
 
0.934
SLC27A5
Bile acyl-CoA synthetase.
   
 
 0.930
DHCR7
7-dehydrocholesterol reductase.
   
 0.907
DHCR24
Delta(24)-sterol reductase.
   
 0.856
SOAT2
O-acyltransferase.
   
 0.824
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 0.812
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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