Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THEMISProtein THEMIS. (639 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
   
 
 0.847
GRAP
GRB2-related adapter protein.
   
 
 0.669
GRAP2
GRB2-related adapter protein 2.
   
 
 0.650
NXPH4
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.542
LAT
Linker for activation of T-cells family member 1.
   
 
 0.505
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.498
LRRTM4
Leucine-rich repeat transmembrane neuronal protein 4.
      
 0.488
SYT6
Synaptotagmin-6 isoform X2.
      
 0.487
HBZ
Hemoglobin subunit zeta; Belongs to the globin family.
      
 0.482
TIFA
TRAF-interacting protein with FHA domain-containing protein A.
      
 0.474
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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