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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCB1Multidrug resistance protein 1. (2440 aa)    
Predicted Functional Partners:
ABCC1
Multidrug resistance-associated protein 1.
   
0.731
ABCC5
Multidrug resistance-associated protein 5 isoform X1.
   
0.662
ABCG2
ATP-binding cassette sub-family G member 2.
   
0.646
ABCC2
Canalicular multispecific organic anion transporter 1.
   
0.628
STEAP3
Metalloreductase STEAP3.
   
  
 0.622
TJP2
Tight junction protein ZO-2 isoform X4; Belongs to the MAGUK family.
      
 0.603
ENSVVUP00000007219
annotation not available
   
 0.589
ABCB7
ATP-binding cassette sub-family B member 7, mitochondrial isoform X1.
    
0.556
OPRM1
Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.533
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
   
  
 0.523
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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