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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase 1 isoform X1.
    
 0.873
SPTLC2
Serine palmitoyltransferase 2 isoform X1.
    
 0.810
SPTLC3
Serine palmitoyltransferase 3.
    
 0.810
ADAM33
Disintegrin and metalloproteinase domain-containing protein 33.
     
 0.609
LRRC3C
Leucine-rich repeat-containing protein 3C.
      
 0.607
ZPBP2
Zona pellucida-binding protein 2.
      
 0.607
PGAP3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
   
  
 0.539
DEGS1
Sphingolipid delta(4)-desaturase DES1.
     
 0.528
DENND1B
DENN domain-containing protein 1B.
      
 0.520
MFSD9
Major facilitator superfamily domain-containing protein 9.
      
 0.517
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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