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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSVVUP00000001492annotation not available (589 aa)    
Predicted Functional Partners:
NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X1.
 
     0.921
EED
Polycomb protein EED isoform X2.
   
 0.610
SUZ12
Polycomb protein SUZ12 isoform X1.
    
 0.547
ASH2L
set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X2.
    
 0.546
RBBP5
Retinoblastoma-binding protein 5.
    
 0.544
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.541
BPTF
Nucleosome-remodeling factor subunit BPTF isoform X2.
  
 
 0.533
BARD1
BRCA1-associated RING domain protein 1.
   
 0.524
KDM6A
Lysine-specific demethylase 6A isoform X1.
   
 0.514
MPHOSPH8
M-phase phosphoprotein 8 isoform X1.
    
 0.490
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.