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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIF21BKinesin-like protein KIF21B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (291 aa)    
Predicted Functional Partners:
ENSVVUP00000001613
annotation not available
 
      0.897
STK36
Serine/threonine-protein kinase 36 isoform X2.
   
 0.809
KIF4A
Chromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
 
 
 0.761
KIF12
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
 
 
 
 0.739
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.716
SUFU
Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]
    
 0.614
WDR26
WD repeat-containing protein 26.
      
 0.607
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
      
 0.606
MKLN1
Muskelin isoform X1.
   
  
 0.564
GLI3
LOW QUALITY PROTEIN: transcriptional activator GLI3.
    
 0.555
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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