HCRTR2 protein (Vulpes vulpes) - STRING interaction network

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Score

HCRTR2

Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)

Predicted Functional Partners:

HCRT

0.997

HCRTR1

0.901

GRK2

0.642

RXFP1

0.618

TRIB2

0.607

GALC

0.607

LSR

0.543

PLCB1

0.527

PLCB2

0.527

ARHGEF25

0.521

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF25	HCRT	ENSVVUP00000023331	ENSVVUP00000028943	Rho guanine nucleotide exchange factor 25 isoform X2.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.518
ARHGEF25	HCRTR1	ENSVVUP00000023331	ENSVVUP00000019842	Rho guanine nucleotide exchange factor 25 isoform X2.	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.408
ARHGEF25	HCRTR2	ENSVVUP00000023331	ENSVVUP00000001609	Rho guanine nucleotide exchange factor 25 isoform X2.	Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.521
GALC	HCRTR2	ENSVVUP00000038420	ENSVVUP00000001609	Galactocerebrosidase isoform X2.	Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.607
GRK2	HCRT	ENSVVUP00000014297	ENSVVUP00000028943	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.517
GRK2	HCRTR1	ENSVVUP00000014297	ENSVVUP00000019842	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.555
GRK2	HCRTR2	ENSVVUP00000014297	ENSVVUP00000001609	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.642
HCRT	ARHGEF25	ENSVVUP00000028943	ENSVVUP00000023331	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	Rho guanine nucleotide exchange factor 25 isoform X2.	0.518
HCRT	GRK2	ENSVVUP00000028943	ENSVVUP00000014297	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.517
HCRT	HCRTR1	ENSVVUP00000028943	ENSVVUP00000019842	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.996
HCRT	HCRTR2	ENSVVUP00000028943	ENSVVUP00000001609	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.997
HCRT	PLCB1	ENSVVUP00000028943	ENSVVUP00000032086	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.586
HCRT	PLCB2	ENSVVUP00000028943	ENSVVUP00000037115	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.547
HCRT	TRIB2	ENSVVUP00000028943	ENSVVUP00000001025	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	Tribbles homolog 2.	0.548
HCRTR1	ARHGEF25	ENSVVUP00000019842	ENSVVUP00000023331	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Rho guanine nucleotide exchange factor 25 isoform X2.	0.408
HCRTR1	GRK2	ENSVVUP00000019842	ENSVVUP00000014297	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.555
HCRTR1	HCRT	ENSVVUP00000019842	ENSVVUP00000028943	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.996
HCRTR1	HCRTR2	ENSVVUP00000019842	ENSVVUP00000001609	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family.	0.901
HCRTR1	PLCB1	ENSVVUP00000019842	ENSVVUP00000032086	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.411
HCRTR1	PLCB2	ENSVVUP00000019842	ENSVVUP00000037115	Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.430