LIPC protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LIPC

Hepatic triacylglycerol lipase. (501 aa)

Predicted Functional Partners:

LIPF

0.947

APOB

0.946

PNPLA2

0.939

PNPLA3

0.925

LPL

0.924

APOE

0.922

MGLL

0.910

CEL

0.908

PNLIPRP3

0.905

PNLIP

0.903

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	APOE	ENSVVUP00000020128	ENSVVUP00000011276	Apolipoprotein B-100.	Apolipoprotein E.	0.975
APOB	LIPC	ENSVVUP00000020128	ENSVVUP00000001665	Apolipoprotein B-100.	Hepatic triacylglycerol lipase.	0.946
APOB	LIPF	ENSVVUP00000020128	ENSVVUP00000001643	Apolipoprotein B-100.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.472
APOB	LPL	ENSVVUP00000020128	ENSVVUP00000036482	Apolipoprotein B-100.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.642
APOE	APOB	ENSVVUP00000011276	ENSVVUP00000020128	Apolipoprotein E.	Apolipoprotein B-100.	0.975
APOE	LIPC	ENSVVUP00000011276	ENSVVUP00000001665	Apolipoprotein E.	Hepatic triacylglycerol lipase.	0.922
APOE	LPL	ENSVVUP00000011276	ENSVVUP00000036482	Apolipoprotein E.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.915
CEL	LIPC	ENSVVUP00000039944	ENSVVUP00000001665	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Hepatic triacylglycerol lipase.	0.908
CEL	LIPF	ENSVVUP00000039944	ENSVVUP00000001643	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.943
CEL	LPL	ENSVVUP00000039944	ENSVVUP00000036482	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.928
CEL	MGLL	ENSVVUP00000039944	ENSVVUP00000025097	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Monoglyceride lipase.	0.918
CEL	PNLIP	ENSVVUP00000039944	ENSVVUP00000014311	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.963
CEL	PNLIPRP3	ENSVVUP00000039944	ENSVVUP00000014300	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.965
CEL	PNPLA2	ENSVVUP00000039944	ENSVVUP00000000123	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	Patatin-like phospholipase domain-containing protein 2.	0.902
CEL	PNPLA3	ENSVVUP00000039944	ENSVVUP00000040087	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3.	0.900
LIPC	APOB	ENSVVUP00000001665	ENSVVUP00000020128	Hepatic triacylglycerol lipase.	Apolipoprotein B-100.	0.946
LIPC	APOE	ENSVVUP00000001665	ENSVVUP00000011276	Hepatic triacylglycerol lipase.	Apolipoprotein E.	0.922
LIPC	CEL	ENSVVUP00000001665	ENSVVUP00000039944	Hepatic triacylglycerol lipase.	Bile salt-activated lipase; Belongs to the type-B carboxylesterase/lipase family.	0.908
LIPC	LIPF	ENSVVUP00000001665	ENSVVUP00000001643	Hepatic triacylglycerol lipase.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.947
LIPC	LPL	ENSVVUP00000001665	ENSVVUP00000036482	Hepatic triacylglycerol lipase.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.924