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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRM3Metabotropic glutamate receptor 3. (879 aa)    
Predicted Functional Partners:
GRM2
Metabotropic glutamate receptor 2 isoform X1.
  
  
0.941
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
   
 0.933
GNAI1
Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X2.
   
 0.933
GNAI2
Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1.
   
 0.933
LOC112932169
Neuroendocrine secretory protein 55.
    
  0.778
GNA12
Guanine nucleotide-binding protein subunit alpha-12.
   
 0.713
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
   
 0.713
AGT
Angiotensinogen; Belongs to the serpin family.
   
 
  0.698
AVP
Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family.
   
 
  0.681
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.674
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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