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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLP1Myelin proteolipid protein isoform X1. (277 aa)    
Predicted Functional Partners:
MBP
Myelin basic protein isoform X3.
   
 
 0.807
SOX10
Transcription factor SOX-10.
   
  
 0.804
GFAP
Glial fibrillary acidic protein isoform X2; Belongs to the intermediate filament family.
   
 
 0.788
PLP2
LOW QUALITY PROTEIN: proteolipid protein 2.
   
 
 0.769
MYRF
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
      
 0.753
ENSVVUP00000005413
annotation not available
   
 
 0.736
CNP
2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.
   
  
 0.715
MAG
Myelin-associated glycoprotein isoform X1.
   
 
 0.669
MOBP
Myelin-associated oligodendrocyte basic protein isoform X1.
   
  
 0.649
MOG
Myelin-oligodendrocyte glycoprotein isoform X1.
   
  
 0.641
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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