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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (166 aa)    
Predicted Functional Partners:
PRKACA
cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.993
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
     
 0.972
PRKACB
cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.
    
 0.969
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
     
 0.944
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
     
 0.942
PPP3CC
Serine/threonine-protein phosphatase.
     
 0.925
PPP3CA
Serine/threonine-protein phosphatase.
     
 0.925
PPP3CB
Serine/threonine-protein phosphatase.
     
 0.925
CDK5
Cyclin-dependent-like kinase 5 isoform X3; Belongs to the protein kinase superfamily.
    
 0.873
ENSVVUP00000020942
annotation not available
     
 0.726
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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