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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM185ATransmembrane protein 185A. (350 aa)    
Predicted Functional Partners:
PAQR5
Membrane progestin receptor gamma.
   
  
 0.616
GPR157
G-protein coupled receptor 157.
      
 0.607
GPR107
Protein GPR107.
      
 0.607
GPR137C
Integral membrane protein GPR137C.
      
 0.607
PAQR8
Membrane progestin receptor beta isoform X1.
   
  
 0.567
PAQR7
Membrane progestin receptor alpha.
   
  
 0.544
GPR108
Protein GPR108.
      
 0.523
GPR149
Probable G-protein coupled receptor 149 isoform X2.
    
 
 0.515
DBNDD2
Dysbindin domain-containing protein 2 isoform X2.
      
 0.456
NOL8
Nucleolar protein 8.
      
 0.448
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.