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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF111E3 ubiquitin-protein ligase Arkadia isoform X2. (994 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog.
   
 0.966
SMAD6
SMAD family member 6.
   
 0.751
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2 isoform X1.
   
 0.682
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 0.677
ENSVVUP00000014764
annotation not available
    
 0.677
UBA52
ubiquitin-60S ribosomal protein L40.
    
 0.659
ENSVVUP00000040094
annotation not available
    
 0.659
LOC112910913
Ubiquitin-like.
    
 0.658
UBC
polyubiquitin-C.
    
 0.658
TRIM35
Tripartite motif-containing protein 35.
   
 
 0.615
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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