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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL21A1-2Collagen alpha-1(XXI) chain isoform X1. (452 aa)    
Predicted Functional Partners:
COL22A1
Collagen alpha-1(XXII) chain.
 
  
 0.939
COL21A1
Collagen alpha-1(XXI) chain isoform X2.
 
      0.899
COL4A6
Collagen alpha-6(IV) chain isoform X1.
 
  
 0.629
COL8A1
Collagen alpha-1(VIII) chain.
 
 
 0.624
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
   
 0.591
COL17A1
Collagen type XVII alpha 1 chain.
     
 0.565
COL26A1
Collagen alpha-1(XXVI) chain.
     
 0.553
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
 0.534
SERPINH1
Serpin H1; Belongs to the serpin family.
   
 0.528
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 isoform X2.
   
 0.521
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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